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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   ANK3 / ANKYRIN-G Antibody (clone S106-20)   

ANK3 / ANKYRIN-G Antibody (clone S106-20)

Mouse Monoclonal Antibody

     
  • IHC - ANK3 / ANKYRIN-G Antibody (clone S106-20) ALS15331
    Anti-ANK3 / ANKYRIN-G antibody IHC of human kidney.
  • IHC - ANK3 / ANKYRIN-G Antibody (clone S106-20) ALS15331
    Anti-ANK3 / ANKYRIN-G antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q12955
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names S106-20
Calculated MW 480kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 288
Other Names Ankyrin-3, ANK-3, Ankyrin-G, ANK3
Target/Specificity Detects over 200kDa.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsANK3 / ANKYRIN-G Antibody (clone S106-20) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANK3
Function In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368).
Cellular Location Cytoplasm, cytoskeleton. Cell projection, axon. Cell membrane, sarcolemma. Cell junction, synapse, postsynaptic cell membrane. Lysosome Note=In skeletal muscle, localized at costameres and neuromuscular junctions. In macrophages, associated with lysosomes
Tissue Location Expressed in brain, neurons, muscles and other tissues.
Volume 50 µl
Research Areas
Citations (0)

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Background

In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (PubMed:23903368).

References

Kordeli E.,et al.J. Biol. Chem. 270:2352-2359(1995).
Devarajan P.,et al.J. Cell Biol. 133:819-830(1996).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS15331
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