|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||ADP/ATP translocase 3, ADP, ATP carrier protein 3, ADP, ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6, ADP/ATP translocase 3, N-terminally processed, SLC25A6, ANT3|
|Target/Specificity||SLC25A6 Antibody detects endogenous levels of total SLC25A6 protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SLC25A6 / ANT3 Antibody (aa121-170) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.|
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Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Cozens A.L.,et al.J. Mol. Biol. 206:261-280(1989).
Zhou J.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (JUL-2004) to UniProtKB.
Houldsworth J.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:377-381(1988).
Verrier F.,et al.Ann. N. Y. Acad. Sci. 1010:126-142(2003).
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