|Application ||WB, IHC-P, E|
|Dilution||ELISA (2-4 µg/ml), IHC-P (10 µg/ml), WB (0.2-0.4 µg/ml)|
|Other Names||Leptin, Obese protein, Obesity factor, LEP, OB, OBS|
|Reconstitution & Storage||Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.|
|Precautions||Leptin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.|
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Provided below are standard protocols that you may find useful for product applications.
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Zhang Y.,et al.Nature 372:425-432(1994).
Zhang Y.,et al.Nature 374:479-479(1995).
Masuzaki H.,et al.Diabetes 44:855-858(1995).
Gong D.W.,et al.J. Biol. Chem. 271:3971-3974(1996).
Chehab F.F.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
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