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CCR3 Antibody (aa5-28)

Goat Polyclonal Antibody

     
  • IHC - CCR3 Antibody (aa5-28) ALS15344
    Anti-CCR3 antibody IHC of human skin.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P51677
Reactivity Human, Mouse
Host Goat
Clonality Polyclonal
Calculated MW 41kDa
Dilution ICC (1:200), IHC-P (5 µg/ml), WB (1:500)
Additional Information
Gene ID 1232
Other Names C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Eosinophil eotaxin receptor, CD193, CCR3, CMKBR3
Target/Specificity This antibody recognizes mouse CCR3 and the peptide sequence is <50 % identical to other chemokine receptors in this region.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCCR3 Antibody (aa5-28) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR3
Synonyms CMKBR3
Function Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location In eosinophils as well as trace amounts in neutrophils and monocytes
Volume 100 µl
Research Areas
Citations (0)

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Background

Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.

References

Combadiere C.,et al.J. Biol. Chem. 270:16491-16494(1995).
Combadiere C.,et al.J. Biol. Chem. 270:30235-30235(1995).
Daugherty B.L.,et al.J. Exp. Med. 183:2349-2354(1996).
Ponath P.D.,et al.J. Exp. Med. 183:2437-2448(1996).
Xiao L.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS15344
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