|Application ||IHC-P, E|
|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Horse, Dog|
|Dilution||ELISA (1:64000), IHC-P (3.75 µg/ml),|
|Other Names||BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873|
|Target/Specificity||Human BAG5. Variants (NP_004864.1; NP_001015048.1) encode the same isoform.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||BAG5 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.|
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Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
Takayama S.,et al.J. Biol. Chem. 274:781-786(1999).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Heilig R.,et al.Nature 421:601-607(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Hasson S.A.,et al.Nature 504:291-295(2013).
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