|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Iduronate 2-sulfatase, 18.104.22.168, Alpha-L-iduronate sulfate sulfatase, Idursulfase, Iduronate 2-sulfatase 42 kDa chain, Iduronate 2-sulfatase 14 kDa chain, IDS, SIDS|
|Target/Specificity||Human IDS. This antibody is expected to recognize isoform a (NP_000193.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||IDS Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.|
|Tissue Location||Liver, kidney, lung, and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
Wilson P.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8531-8535(1990).
Wilson P.J.,et al.Genomics 17:773-775(1993).
Timms K.M.,et al.Genome Res. 5:71-78(1995).
Malmgren H.,et al.Genomics 29:291-293(1995).
Ross M.T.,et al.Nature 434:325-337(2005).
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