IDS Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P22304 |
Reactivity | Human, Monkey |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 62kDa |
Dilution | ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 3423 |
---|---|
Other Names | Iduronate 2-sulfatase, 3.1.6.13, Alpha-L-iduronate sulfate sulfatase, Idursulfase, Iduronate 2-sulfatase 42 kDa chain, Iduronate 2-sulfatase 14 kDa chain, IDS, SIDS |
Target/Specificity | Human IDS. This antibody is expected to recognize isoform a (NP_000193.1). |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | IDS Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IDS |
---|---|
Synonyms | SIDS |
Function | Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. |
Cellular Location | Lysosome. |
Tissue Location | Liver, kidney, lung, and placenta. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
References
Wilson P.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8531-8535(1990).
Wilson P.J.,et al.Genomics 17:773-775(1993).
Timms K.M.,et al.Genome Res. 5:71-78(1995).
Malmgren H.,et al.Genomics 29:291-293(1995).
Ross M.T.,et al.Nature 434:325-337(2005).
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