|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains, BAG4, SODD|
|Target/Specificity||Human BAG4 / SODD.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||BAG4 / SODD Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.
Takayama S.,et al.J. Biol. Chem. 274:781-786(1999).
Jiang Y.,et al.Science 283:543-546(1999).
Jiang Y.,et al.Science 283:1852-1852(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
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