|Application ||WB, IHC-P, Flo|
|Dilution||IHC-P (5-10 µg/ml), WB (0.2-2 µg/ml),|
|Other Names||Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17A, CTLA8, IL17|
|Target/Specificity||Human IL17A / IL-17|
|Reconstitution & Storage||Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.|
|Precautions||IL17A Antibody (aa1-75, clone 4K5F6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).|
|Tissue Location||Restricted to activated memory T-cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
Fossiez F.,et al.J. Exp. Med. 183:2593-2603(1996).
Yao Z.,et al.J. Immunol. 155:5483-5486(1995).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
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