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SOX3 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P41225 |
| Reactivity | Human, Mouse, Rabbit, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Dilution | ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.5-1.5 µg/ml) |
| Gene ID | 6658 |
|---|---|
| Other Names | Transcription factor SOX-3, SOX3 |
| Target/Specificity | Human SOX3. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | SOX3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOX3 |
|---|---|
| Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).
References
Stevanovic M.,et al.Hum. Mol. Genet. 2:2013-2018(1993).
Gorry M.C.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Denny P.,et al.Nucleic Acids Res. 20:2887-2887(1992).
Sutton E.,et al.J. Clin. Invest. 121:328-341(2011).
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