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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARHGDIG / RHOGDI-3 Antibody (C-Terminus)   

ARHGDIG / RHOGDI-3 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - ARHGDIG / RHOGDI-3 Antibody (C-Terminus) ALS15383
    ARHGDIG antibody (0.5 ug/ml) staining of HeLa lysate (35 ug protein/ml in RIPA buffer).
  • IHC - ARHGDIG / RHOGDI-3 Antibody (C-Terminus) ALS15383
    Anti-ARHGDIG / RHOGDI-3 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99819
Reactivity Human, Monkey, Dog
Host Goat
Clonality Polyclonal
Calculated MW 25kDa
Dilution ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.5-2 µg/ml)
Additional Information
Gene ID 398
Other Names Rho GDP-dissociation inhibitor 3, Rho GDI 3, Rho-GDI gamma, ARHGDIG
Target/Specificity Human ARHGDIG.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsARHGDIG / RHOGDI-3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARHGDIG
Function Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Cellular Location Cytoplasm.
Tissue Location Primarily expressed in pancreas and brain.
Research Areas
Citations (0)

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Background

Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

References

Adra C.N.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4279-4284(1997).
Adra C.N.,et al.Genomics 53:104-109(1998).
Hayashi A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).

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$ 395.00
Cat# ALS15383
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