|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23|
|Target/Specificity||Human SNAP23. This antibody is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SNAP23 / SNAP-23 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome Note=Mainly localized to the plasma membrane|
|Tissue Location||Ubiquitous. Highest levels where found in placenta|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Ravichandran V.,et al.J. Biol. Chem. 271:13300-13303(1996).
Mollinedo F.,et al.Biochem. Biophys. Res. Commun. 231:808-812(1997).
Lazo P.A.,et al.Hum. Genet. 108:211-215(2001).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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