|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:20000), IF (1:100-1:500), IHC-P (5 µg/ml), WB (1:500-1:1000) ,|
|Other Names||Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37, Hsp90 co-chaperone Cdc37, N-terminally processed, CDC37, CDC37A|
|Target/Specificity||CDC37 (Ab-13) Antibody detects endogenous levels of total CDC37 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||CDC37 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206).|
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Provided below are standard protocols that you may find useful for product applications.
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
Stepanova L.,et al.Genes Dev. 10:1491-1502(1996).
Dai K.,et al.J. Biol. Chem. 271:22030-22034(1996).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Lamphere L.,et al.Oncogene 14:1999-2004(1997).
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