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>   home   >   Products   >   Primary Antibodies   >   AP-2 Alpha/Beta Antibody (aa388-437)   

AP-2 Alpha/Beta Antibody (aa388-437)

Rabbit Polyclonal Antibody

     
  • WB - AP-2 Alpha/Beta Antibody (aa388-437) ALS15418
    Western blot of extracts from COLO205 cells, using AP-2 Antibody.
    detail
  • IHC - AP-2 Alpha/Beta Antibody (aa388-437) ALS15418
    Anti-AP-2 Alpha/Beta antibody IHC of human placenta.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P05549
Other Accession O95782, O94973, P63010, Q92481
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 48062 Da
Dilution ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 7020
Other Names Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, TFAP2A, AP2TF, TFAP2
Target/Specificity AP-2 Antibody detects endogenous levels of total AP-2 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsAP-2 Alpha/Beta Antibody (aa388-437) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFAP2A
Synonyms AP2TF, TFAP2
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
Cellular Location Nucleus.
Volume 50 µl
Citations (0)
citation

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Discontinued
Cat# ALS15418
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