|Application ||WB, IHC-P, IF, E|
|Dilution||ELISA (1:10000), IF (1:100-1:500), IHC-P (5 µg/ml), WB (1:500-1:1000) ,|
|Other Names||Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, HSPH1, HSP105, HSP110, KIAA0201|
|Target/Specificity||HSP105 Antibody detects endogenous levels of total HSP105 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||HSPH1 / HSP110 Antibody (aa791-840) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||HSP105, HSP110, KIAA0201|
|Function||Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).|
|Tissue Location||Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.|
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Provided below are standard protocols that you may find useful for product applications.
Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
Ishihara K.,et al.Biochim. Biophys. Acta 1444:138-142(1999).
Scanlan M.J.,et al.Int. J. Cancer 76:652-658(1998).
Nagase T.,et al.DNA Res. 3:321-329(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
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