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PRAF2 Antibody (aa129-178)

Rabbit Polyclonal Antibody

     
  • WB - PRAF2 Antibody (aa129-178) ALS15425
    Western blot of extracts from LOVO cells, using JM4 Antibody.
    detail
  • IHC - PRAF2 Antibody (aa129-178) ALS15425
    Anti-JM4 / PRAF2 antibody IHC of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O60831
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 19kDa
Dilution ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 11230
Other Names PRA1 family protein 2, PRAF2
Target/Specificity JM4 Antibody detects endogenous levels of total JM4 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsPRAF2 Antibody (aa129-178) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRAF2
Function May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis.
Cellular Location Endosome membrane; Multi-pass membrane protein
Tissue Location Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.

References

Strom T.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Schweneker M.,et al.FEBS Lett. 579:1751-1758(2005).

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Discontinued
Cat# ALS15425
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