|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:20000), IF (1:100-1:500), IHC-P (5 µg/ml), WB (1:500-1:1000) ,|
|Other Names||A-kinase anchor protein 8, AKAP-8, A-kinase anchor protein 95 kDa, AKAP 95, AKAP8, AKAP95|
|Target/Specificity||AKAP8 Antibody detects endogenous levels of total AKAP8 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||AKAP8 / AKAP95 Antibody (aa331-380) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).|
|Cellular Location||Nucleus matrix. Note=Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis|
|Tissue Location||Highly expressed in heart, liver, skeletal muscle, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).
Eide T.,et al.Exp. Cell Res. 238:305-316(1998).
Grimwood J.,et al.Nature 428:529-535(2004).
Olsen J.V.,et al.Cell 127:635-648(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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