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RAB4A / RAB4 Antibody

Rabbit Polyclonal Antibody

     
  • WB - RAB4A / RAB4 Antibody ALS15444
    Rab4, Hela.
    detail
  • IHC - RAB4A / RAB4 Antibody ALS15444
    Anti-Ras-related protein Rab-4 (RAB4) antibody IHC of human liver.
    detail
  • IHC - RAB4A / RAB4 Antibody ALS15444
    Anti-Ras-related protein Rab-4 (RAB4) antibody IHC of human pancreas.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P20338
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 24kDa
Dilution IHC-P (1:200), WB (1:1000-1:2000),
Additional Information
Gene ID 5867
Other Names Ras-related protein Rab-4A, RAB4A, RAB4
Target/Specificity Detects ~26 kD protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsRAB4A / RAB4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB4A
Synonyms RAB4
Function Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity).
Cellular Location Membrane; Peripheral membrane protein. Cytoplasm Early endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Recycling endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Protein transport. Probably involved in vesicular traffic (By similarity).

References

Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Nagy G.,et al.J. Biol. Chem. 281:34574-34591(2006).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 467.50
Cat# ALS15444
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