|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER, NAB2, MADER|
|Target/Specificity||NAB2 Antibody detects endogenous levels of total NAB2 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||NAB2 Antibody (aa261-310) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).|
|Cellular Location||Nucleus. Note=Isoform 2 is not localized to the nucleus.|
|Tissue Location||Widely expressed at low levels. Highly expressed in melanoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).
Svaren J.,et al.Mol. Cell. Biol. 16:3545-3553(1996).
Gerlinger M.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Kirsch K.H.,et al.Oncogene 12:963-971(1996).
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