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TRERF1 Antibody (aa1071-1120)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | Q96PN7 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 132kDa |
| Dilution | ELISA (1:1000), IHC-P (5 µg/ml), |
| Gene ID | 55809 |
|---|---|
| Other Names | Transcriptional-regulating factor 1, Breast cancer anti-estrogen resistance 2, Transcriptional-regulating protein 132, Zinc finger protein rapa, Zinc finger transcription factor TReP-132, TRERF1, BCAR2, RAPA, TREP132 |
| Target/Specificity | TREF1 Antibody detects endogenous levels of total TREF1 protein. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | TRERF1 Antibody (aa1071-1120) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRERF1 |
|---|---|
| Synonyms | BCAR2, RAPA, TREP132 |
| Function | Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:11349124, ECO:0000269|PubMed:16371131} |
| Tissue Location | Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
References
Gizard F.,et al.J. Biol. Chem. 276:33881-33892(2001).
Mauch S.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
van Agthoven T.,et al.Breast Cancer Res. Treat. 114:23-30(2009).
Mungall A.J.,et al.Nature 425:805-811(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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