|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||Mitochondrial 2-oxodicarboxylate carrier, Solute carrier family 25 member 21, SLC25A21, ODC|
|Target/Specificity||SLC25A21 Antibody detects endogenous levels of total SLC25A21 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||SLC25A21 / ODC1 Antibody (aa134-183) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.
Fiermonte G.,et al.J. Biol. Chem. 276:8225-8230(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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