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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RAB3GAP1 Antibody (aa538-587)   

RAB3GAP1 Antibody (aa538-587)

Rabbit Polyclonal Antibody

     
  • WB - RAB3GAP1 Antibody (aa538-587) ALS15515
    Western blot of extracts from 293 cells, using RAB3GAP1 Antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q15042
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 111kDa
Dilution ELISA (1:40000), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 22930
Other Names Rab3 GTPase-activating protein catalytic subunit, RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, RAB3GAP1, KIAA0066, RAB3GAP
Target/Specificity RAB3GAP1 Antibody detects endogenous levels of total RAB3GAP1 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsRAB3GAP1 Antibody (aa538-587) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB3GAP1
Synonyms KIAA0066, RAB3GAP
Function Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Cellular Location Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction
Tissue Location Ubiquitous..
Volume 50 µl
Research Areas
Citations (0)

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Background

Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

References

Nomura N.,et al.DNA Res. 1:223-229(1994).
Hillier L.W.,et al.Nature 434:724-731(2005).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Fukui K.,et al.J. Biol. Chem. 272:4655-4658(1997).
Oishi H.,et al.J. Biol. Chem. 273:34580-34585(1998).

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$ 395.00
Cat# ALS15515
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