|Application ||IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:10000), IHC-P (1:50-1:100),|
|Other Names||SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3, NSHC, SHCC|
|Target/Specificity||SHC3 Antibody detects endogenous levels of total SHC3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||SHC3 / SHCC Antibody (aa291-340) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.|
|Tissue Location||Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Nakamura T.,et al.Oncogene 13:1111-1121(1996).
Pelicci G.,et al.Oncogene 13:633-641(1996).
Humphray S.J.,et al.Nature 429:369-374(2004).
Liu H.Y.,et al.J. Biol. Chem. 277:26046-26056(2002).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.