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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SHC3 / SHCC Antibody (aa291-340)   

SHC3 / SHCC Antibody (aa291-340)

Rabbit Polyclonal Antibody

     
  • IHC - SHC3 / SHCC Antibody (aa291-340) ALS15520
    Anti-SHC3 / SHCC antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q92529
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 64kDa
Dilution ELISA (1:10000), IHC-P (1:50-1:100),
Additional Information
Gene ID 53358
Other Names SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3, NSHC, SHCC
Target/Specificity SHC3 Antibody detects endogenous levels of total SHC3 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsSHC3 / SHCC Antibody (aa291-340) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SHC3
Synonyms NSHC, SHCC
Function Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Tissue Location Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord
Volume 50 µl
Research Areas
Citations (0)

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Background

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

References

Nakamura T.,et al.Oncogene 13:1111-1121(1996).
Pelicci G.,et al.Oncogene 13:633-641(1996).
Humphray S.J.,et al.Nature 429:369-374(2004).
Liu H.Y.,et al.J. Biol. Chem. 277:26046-26056(2002).

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$ 395.00
Cat# ALS15520
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