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SCAR2 / WAVE2 Antibody (aa190-239)

Rabbit Polyclonal Antibody

     
  • IHC - SCAR2 / WAVE2 Antibody (aa190-239) ALS15526
    Anti-SCAR2 / WAVE2 antibody IHC of human lung.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9Y6W5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution ELISA (1:10000), IHC-P (5 µg/ml),
Additional Information
Gene ID 10163
Other Names Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2
Target/Specificity WASF4 Antibody detects endogenous levels of total WASF4 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsSCAR2 / WAVE2 Antibody (aa190-239) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WASF2
Synonyms WAVE2
Function Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
Cellular Location Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=At the interface between the lamellipodial actin meshwork and the membrane
Tissue Location Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.
Volume 50 µl
Research Areas
Citations (0)

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Background

Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

References

Suetsugu S.,et al.Biochem. Biophys. Res. Commun. 260:296-302(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Miki H.,et al.Nature 408:732-735(2000).
Gautreau A.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:4379-4383(2004).

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$ 395.00
Cat# ALS15526
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