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NPR3 Antibody (aa520-533)

Goat Polyclonal Antibody

     
  • WB - NPR3 Antibody (aa520-533) ALS15556
    NPR3 antibody (1 ug/ml) staining of Human Placenta lysate (35 ug protein in RIPA buffer).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P17342
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 60kDa
Dilution ELISA (1:16000), IHC-P (10 µg/ml), WB (1-3 µg/ml)
Additional Information
Gene ID 4883
Other Names Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC
Target/Specificity Human NPR3. The immunizing peptide represents the cytoplasmic part of the protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsNPR3 Antibody (aa520-533) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPR3
Synonyms ANPRC, C5orf23, NPRC
Function Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.

References

Lowe D.G.,et al.Nucleic Acids Res. 18:3412-3412(1990).
Porter J.G.,et al.Biochem. Biophys. Res. Commun. 171:796-803(1990).
Rae J.L.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).

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$ 395.00
Cat# ALS15556
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