|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (0.5-4 µg/ml),|
|Other Names||Caspase-6, CASP-6, 220.127.116.11, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2|
|Target/Specificity||The antibody detects a full length (35 kD) and the cleaved fragment (18 kD) of caspase-6. Blocking Peptide is available separately.|
|Reconstitution & Storage||Long term: -70°C; Short term: -20°C|
|Precautions||CASP6 / Caspase 6 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Fernandes-Alnemri T.,et al.Cancer Res. 55:2737-2742(1995).
Srinivasula S.M.,et al.J. Biol. Chem. 271:27099-27106(1996).
Bartke T.,et al.Mol. Cell 14:801-811(2004).
Suzuki A.,et al.Oncogene 23:7067-7075(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.