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ZBTB16 / PLZF Antibody (clone 5B3)

Mouse Monoclonal Antibody

     
  • IHC - ZBTB16 / PLZF Antibody (clone 5B3) ALS15573
    Anti-ZBTB16 / PLZF antibody IHC staining of human adrenal.
  • IF - ZBTB16 / PLZF Antibody (clone 5B3) ALS15573
    Immunofluorescence of HeLa cells using ZBTB16 mouse monoclonal antibody (green).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC, E
Primary Accession Q05516
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5B3
Calculated MW 74kDa
Dilution ELISA (1:10000), ICC (1:200-1:1000), IF (1:1000), IHC-P (1:50), WB (1:500-1:2000)
Additional Information
Gene ID 7704
Other Names Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, ZBTB16, PLZF, ZNF145
Target/Specificity Human PLZF
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsZBTB16 / PLZF Antibody (clone 5B3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB16
Synonyms PLZF, ZNF145
Function Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Cellular Location Nucleus.
Tissue Location Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung
Research Areas
Citations (0)

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Background

Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

References

Chen Z.,et al.EMBO J. 12:1161-1167(1993).
Zhang T.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:11422-11427(1999).
Chen S.-J.,et al.J. Clin. Invest. 91:2260-2267(1993).
Hoatlin M.E.,et al.Blood 94:3737-3747(1999).
Itoh T.,et al.Science 291:1047-1051(2001).

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$ 395.00
Cat# ALS15573
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