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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STAT5A Antibody   

STAT5A Antibody

Rabbit Polyclonal Antibody

     
  • IHC - STAT5A Antibody ALS15575
    Anti-STAT5A antibody IHC staining of human breast.
  • WB - STAT5A Antibody ALS15575
    Western blot of 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2) with STAT5A /...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession P42229
Reactivity Human, Mouse, Rat, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 91kDa
Dilution IHC-P (5 µg/ml), IP (20 µg/ml), WB (2-10 µg/ml)
Additional Information
Gene ID 6776
Other Names Signal transducer and activator of transcription 5A, STAT5A, STAT5
Target/Specificity The antibody recognizes ~95 kD Stat5 of human, mouse and rat origins. Reactivity to other species has not been tested.
Reconstitution & Storage Short term +4°C (no longer than one week); Long term -20°C; Aliquot to avoid freeze/thaw cycles.
PrecautionsSTAT5A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAT5A
Synonyms STAT5
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Cellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation
Research Areas
Citations (0)

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Background

Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

References

Hou J.,et al.Immunity 2:321-329(1995).
Lin J.X.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Tan D.,et al.Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 395.00
Cat# ALS15575
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