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STAT5A Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | P42229 |
| Reactivity | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 91kDa |
| Dilution | IHC-P (5 µg/ml), IP (20 µg/ml), WB (2-10 µg/ml) |
| Gene ID | 6776 |
|---|---|
| Other Names | Signal transducer and activator of transcription 5A, STAT5A, STAT5 |
| Target/Specificity | The antibody recognizes ~95 kD Stat5 of human, mouse and rat origins. Reactivity to other species has not been tested. |
| Reconstitution & Storage | Short term +4°C (no longer than one week); Long term -20°C; Aliquot to avoid freeze/thaw cycles. |
| Precautions | STAT5A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STAT5A |
|---|---|
| Synonyms | STAT5 |
| Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation. |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
References
Hou J.,et al.Immunity 2:321-329(1995).
Lin J.X.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Tan D.,et al.Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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