|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (0.5-4 µg/ml),|
|Other Names||1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2, 220.127.116.11, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2|
|Target/Specificity||The antibody recognizes 139 kD human PLC gamma 1 &2. Jurkat cell lysate can be used as a positive control. Reactivity to other species has not been determined.|
|Reconstitution & Storage||Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.|
|Precautions||PLCG2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.|
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Provided below are standard protocols that you may find useful for product applications.
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Ohta S.,et al.FEBS Lett. 242:31-35(1988).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Kemmer D.,et al.BMC Genomics 7:48-48(2006).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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