|Application ||IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39|
|Target/Specificity||Recognizes C-myc in human nuclear protein. Nuclear protein involved in regulation of cell cycle and apoptosis.|
|Reconstitution & Storage||May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.|
|Precautions||MYC / c-Myc Antibody (aa408-420) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.|
|Cellular Location||Nucleus, nucleoplasm. Nucleus, nucleolus|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Battey J.,et al.Cell 34:779-787(1983).
Bernard O.,et al.EMBO J. 2:2375-2383(1983).
Colby W.W.,et al.Nature 301:722-725(1983).
Watt R.,et al.Nature 303:725-728(1983).
Rabbitts T.H.,et al.Nature 306:760-765(1983).
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