|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Tenascin, TN, Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, JI, Myotendinous antigen, Neuronectin, Tenascin-C, TN-C, TNC, HXB|
|Target/Specificity||Human TNC / Tenascin C|
|Reconstitution & Storage||Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.|
|Precautions||TNC / Tenascin C Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Nies D.E.,et al.J. Biol. Chem. 266:2818-2823(1991).
Siri A.,et al.Nucleic Acids Res. 19:525-531(1991).
Gulcher J.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:9438-9442(1991).
Gherzi R.,et al.J. Biol. Chem. 270:3429-3434(1995).
Humphray S.J.,et al.Nature 429:369-374(2004).
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