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TTYH2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - TTYH2 Antibody (N-Terminus) ALS15627
    Anti-TTYH2 antibody IHC staining of human heart.
    detail
  • IF - TTYH2 Antibody (N-Terminus) ALS15627
    Immunofluorescence of TTYH2 in human kidney tissue with TTYH2 antibody at 20 ug/ml.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9BSA4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 59kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 94015
Other Names Protein tweety homolog 2, hTTY2, TTYH2, C17orf29
Target/Specificity Human TTYH2. At least four isoforms of TTYH2 are known to exist; this antibody will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members.
Reconstitution & Storage Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsTTYH2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTYH2
Synonyms C17orf29
Function Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma
Citations (0)
citation

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Background

Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.

References

Rae F.K.,et al.Genomics 77:200-207(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Suzuki M.,et al.J. Biol. Chem. 279:22461-22468(2004).

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Discontinued
Cat# ALS15627
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