TTYH2 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | Q9BSA4 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 94015 |
---|---|
Other Names | Protein tweety homolog 2, hTTY2, TTYH2, C17orf29 |
Target/Specificity | Human TTYH2. At least four isoforms of TTYH2 are known to exist; this antibody will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members. |
Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | TTYH2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TTYH2 |
---|---|
Synonyms | C17orf29 |
Function | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
References
Rae F.K.,et al.Genomics 77:200-207(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Suzuki M.,et al.J. Biol. Chem. 279:22461-22468(2004).
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