|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Protein tweety homolog 2, hTTY2, TTYH2, C17orf29|
|Target/Specificity||Human TTYH2. At least four isoforms of TTYH2 are known to exist; this antibody will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members.|
|Reconstitution & Storage||Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||TTYH2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma|
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Provided below are standard protocols that you may find useful for product applications.
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
Rae F.K.,et al.Genomics 77:200-207(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Suzuki M.,et al.J. Biol. Chem. 279:22461-22468(2004).
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