STOX1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
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Primary Accession | Q6ZVD7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 111kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 219736 |
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Other Names | Storkhead-box protein 1, Winged-helix domain-containing protein, STOX1, C10orf24 |
Target/Specificity | Human STOX1. STOX1 antibody is human reactive. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. STOX1 antibody recognize the longest isoform. |
Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | STOX1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STOX1 |
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Synonyms | C10orf24 |
Function | Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (PubMed:24738702). Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway (By similarity). |
Cellular Location | [Isoform A]: Cytoplasm. Nucleus Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In epithelial cells, diffusely expressed in the cytoplasm, particularly in peri-membrane cortical regions (By similarity). Concentrated at centrosomes during metaphase (PubMed:22253775). {ECO:0000250|UniProtKB:B2RQL2, ECO:0000269|PubMed:22253775} [Isoform C]: Nucleus, nucleolus. |
Tissue Location | Expressed in placenta, including the invasive extravillus trophoblast cells. |
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Provided below are standard protocols that you may find useful for product applications.
References
van Dijk M.,et al.Nat. Genet. 37:514-519(2005).
Deloukas P.,et al.Nature 429:375-381(2004).
van Dijk M.,et al.Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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