RGS22 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | Q8NE09 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 147kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 26166 |
---|---|
Other Names | Regulator of G-protein signaling 22, RGS22, RGS22 |
Target/Specificity | Human RGS22. At least four isoforms of RGS22 are known to exist; this antibody will detect the three longest isoforms. RGS22 antibody is predicted to not cross-react with other RGS proteins. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | RGS22 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RGS22 |
---|---|
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
Cellular Location | Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus |
Tissue Location | Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
References
Hu Y.,et al.Biol. Reprod. 79:1021-1029(2008).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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