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SGSM1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - SGSM1 Antibody (Internal) ALS15660
    Anti-SGSM1 antibody IHC staining of human pancreas.
  • IF - SGSM1 Antibody (Internal) ALS15660
    Immunofluorescence of SGSM1 in human brain tissue with SGSM1 antibody at 20 ug/ml.
  • WB - SGSM1 Antibody (Internal) ALS15660
    Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody at 1 ug/ml...
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q2NKQ1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 130kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 129049
Other Names Small G protein signaling modulator 1, RUN and TBC1 domain-containing protein 2, SGSM1, KIAA1941, RUTBC2
Target/Specificity Human SGSM1. At least four isoforms of SGSM1 are known to exist; SGSM1 antibody will detect all four isoforms.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsSGSM1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SGSM1
Synonyms KIAA1941, RUTBC2
Function Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.
Cellular Location Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q8BPQ7}. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm. Note=Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A.
Tissue Location Mainly expressed in brain, heart and testis.
Research Areas
Citations (0)

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References

Yang H.,et al.Genomics 90:249-260(2007).
Ishibashi K.,et al.Genes Cells 14:41-52(2009).
Nagase T.,et al.DNA Res. 8:319-327(2001).
Dunham I.,et al.Nature 402:489-495(1999).

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$ 395.00
Cat# ALS15660
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