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SGSM1 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | Q2NKQ1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 130kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 129049 |
|---|---|
| Other Names | Small G protein signaling modulator 1, RUN and TBC1 domain-containing protein 2, SGSM1, KIAA1941, RUTBC2 |
| Target/Specificity | Human SGSM1. At least four isoforms of SGSM1 are known to exist; SGSM1 antibody will detect all four isoforms. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SGSM1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SGSM1 |
|---|---|
| Synonyms | KIAA1941, RUTBC2 |
| Function | Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B. |
| Cellular Location | Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q8BPQ7}. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm Note=Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A. |
| Tissue Location | Mainly expressed in brain, heart and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Yang H.,et al.Genomics 90:249-260(2007).
Ishibashi K.,et al.Genes Cells 14:41-52(2009).
Nagase T.,et al.DNA Res. 8:319-327(2001).
Dunham I.,et al.Nature 402:489-495(1999).
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