FOXH1 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | O75593 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 8928 |
---|---|
Other Names | Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1, hFAST-1, Forkhead activin signal transducer 2, Fast-2, FOXH1, FAST1, FAST2 |
Target/Specificity | Human FOXH1. FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | FOXH1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FOXH1 |
---|---|
Synonyms | FAST1, FAST2 |
Function | Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
References
Zhou S.,et al.Mol. Cell 2:121-127(1998).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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