|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||ZW10 interactor, ZW10-interacting protein 1, Zwint-1, ZWINT|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||ZWINT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.|
|Cellular Location||Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase|
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Provided below are standard protocols that you may find useful for product applications.
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
Starr D.A.,et al.J. Cell Sci. 113:1939-1950(2000).
Deloukas P.,et al.Nature 429:375-381(2004).
Musio A.,et al.Gene 331:33-40(2004).
Wang H.,et al.J. Biol. Chem. 279:54590-54598(2004).
Obuse C.,et al.Nat. Cell Biol. 6:1135-1141(2004).
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