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ZWINT Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O95229 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 31kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:500-1:3000), |
| Gene ID | 11130 |
|---|---|
| Other Names | ZW10 interactor, ZW10-interacting protein 1, Zwint-1, ZWINT |
| Target/Specificity | Human ZWINT. |
| Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Precautions | ZWINT Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZWINT |
|---|---|
| Function | Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. |
| Cellular Location | Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
References
Starr D.A.,et al.J. Cell Sci. 113:1939-1950(2000).
Deloukas P.,et al.Nature 429:375-381(2004).
Musio A.,et al.Gene 331:33-40(2004).
Wang H.,et al.J. Biol. Chem. 279:54590-54598(2004).
Obuse C.,et al.Nat. Cell Biol. 6:1135-1141(2004).
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