|Application ||IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Cryptic protein, Cryptic family protein 1, CFC1|
|Reconstitution & Storage||Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.|
|Precautions||CFC1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI- signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates|
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Provided below are standard protocols that you may find useful for product applications.
NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.
Bamford R.N.,et al.Nat. Genet. 26:365-369(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Watanabe K.,et al.Biochim. Biophys. Acta 1778:2671-2681(2008).
Goldmuntz E.,et al.Am. J. Hum. Genet. 70:776-780(2002).
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