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GREM2 / Gremlin 2 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - GREM2 / Gremlin 2 Antibody ALS15701
    Anti-GREM2 / Gremlin 2 antibody IHC staining of human prostate.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9H772
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 19kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 64388
Other Names Gremlin-2, Cysteine knot superfamily 1, BMP antagonist 2, DAN domain family member 3, Protein related to DAN and cerberus, GREM2, CKTSF1B2, DAND3, PRDC
Target/Specificity Human GREM2 / Gremlin 2
Reconstitution & Storage Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
PrecautionsGREM2 / Gremlin 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GREM2
Synonyms CKTSF1B2, DAND3, PRDC
Function Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.
Cellular Location Secreted.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity).

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Katoh M.,et al.Oncol. Rep. 12:423-427(2004).

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$ 467.50
Cat# ALS15701
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