|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:3000),|
|Other Names||Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, p53-induced gene 7 protein, LITAF, PIG7, SIMPLE|
|Target/Specificity||Human LITAF. Predicted cross-reactivity based on amino acid sequence homology: mouse (85%), rat (86%), bovine (86%).|
|Reconstitution & Storage||Aliquot and store at -20°C. Minimize freezing and thawing.|
|Precautions||LITAF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF- alpha) gene expression.|
|Cellular Location||Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with membranes of lysosomes|
|Tissue Location||Ubiquitously and abundantly expressed. Expressed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF- alpha) gene expression.
Polyak K.,et al.Nature 389:300-306(1997).
Myokai F.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:4518-4523(1999).
Moriwaki Y.,et al.J. Biol. Chem. 276:23065-23076(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.