|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1:1000),|
|Other Names||Sialic acid synthase, N-acetylneuraminate synthase, 18.104.22.168, N-acetylneuraminate-9-phosphate synthase, 22.214.171.124, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthase, NANS, SAS|
|Reconstitution & Storage||Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.|
|Precautions||NANS Antibody (clone AT1G6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.|
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Provided below are standard protocols that you may find useful for product applications.
Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
Lawrence S.M.,et al.J. Biol. Chem. 275:17869-17877(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
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