NANS Antibody (clone AT1G6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9NR45 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | AT1G6 |
Calculated MW | 40kDa |
Dilution | IHC-P (10 µg/ml), WB (1:1000), |
Gene ID | 54187 |
---|---|
Other Names | Sialic acid synthase, N-acetylneuraminate synthase, 2.5.1.56, N-acetylneuraminate-9-phosphate synthase, 2.5.1.57, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthase, NANS, SAS |
Target/Specificity | Human NANS |
Reconstitution & Storage | Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |
Precautions | NANS Antibody (clone AT1G6) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NANS |
---|---|
Synonyms | SAS |
Function | Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy- D-glycero-D-galacto-nononic acid (KDN) (PubMed:10749855, PubMed:27213289). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively (PubMed:10749855). |
Tissue Location | Ubiquitous.. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
References
Lawrence S.M.,et al.J. Biol. Chem. 275:17869-17877(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
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