PPIC / Cyclophilin C Antibody (clone AT3C6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | P45877 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | AT3C6 |
Calculated MW | 23kDa |
Dilution | IHC-P (10 µg/ml), WB (1:1000), |
Gene ID | 5480 |
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Other Names | Peptidyl-prolyl cis-trans isomerase C, PPIase C, 5.2.1.8, Cyclophilin C, Rotamase C, PPIC, CYPC |
Target/Specificity | Human PPIC / Cyclophilin C |
Reconstitution & Storage | Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |
Precautions | PPIC / Cyclophilin C Antibody (clone AT3C6) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PPIC (HGNC:9256) |
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Synonyms | CYPC |
Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P30412}. |
Tissue Location | Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
References
Schneider H.,et al.Biochemistry 33:8218-8224(1994).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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