Insulin Antibody (clone E2E3)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E, IHC-Fr |
---|---|
Primary Accession | P01308 |
Reactivity | Human, Rabbit, Pig, Bovine |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | E2E3 |
Calculated MW | 12kDa |
Dilution | IHC-Fr (1:50-1:100), IHC-P (10 µg/ml), |
Gene ID | 3630 |
---|---|
Other Names | Insulin, Insulin B chain, Insulin A chain, INS |
Target/Specificity | Recognizes insulin, a major metabolic hormone produced by B cells of the pancreas |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | Insulin Antibody (clone E2E3) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | INS |
---|---|
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
Cellular Location | Secreted. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
References
Bell G.I.,et al.Nature 284:26-32(1980).
Ullrich A.,et al.Science 209:612-615(1980).
Bell G.I.,et al.Nature 282:525-527(1979).
Sures I.,et al.Science 208:57-59(1980).
Lucassen A.M.,et al.Nat. Genet. 4:305-310(1993).
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