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ATF1 Antibody (aa176-225)

Rabbit Polyclonal Antibody

     
  • IF - ATF1 Antibody (aa176-225) ALS15755
    Immunofluorescence of HUVEC cells, using ATF1 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P18846
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:5000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 466
Other Names Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1
Target/Specificity ATF1 Antibody detects endogenous levels of total ATF1 protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsATF1 Antibody (aa176-225) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF1
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Cellular Location Nucleus.
Volume 50 µl
Citations (0)

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Background

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

References

Yoshimura T.,et al.EMBO J. 9:2537-2542(1990).
Rehfuss R.P.,et al.J. Biol. Chem. 266:18431-18434(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Hai T.,et al.Genes Dev. 3:2083-2090(1989).

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$ 395.00
Cat# ALS15755
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