|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:20000), IF (1:100-1:500), IHC-P (20 µg/ml), WB (1:500-1:1000) ,|
|Other Names||Glycerol kinase, GK, Glycerokinase, 220.127.116.11, ATP:glycerol 3-phosphotransferase, GK|
|Target/Specificity||GK Antibody detects endogenous levels of total GK protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||GK / Glycerol Kinase Antibody (aa461-510) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme in the regulation of glycerol uptake and metabolism.|
|Cellular Location||Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm|
|Tissue Location||Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver|
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Provided below are standard protocols that you may find useful for product applications.
Key enzyme in the regulation of glycerol uptake and metabolism.
Guo W.,et al.Nat. Genet. 4:367-372(1993).
Sargent C.A.,et al.Hum. Mol. Genet. 3:1317-1324(1994).
Sargent C.A.,et al.J. Med. Genet. 37:434-441(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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