TXNDC5 / ERP46 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q8NBS9 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 48kDa |
Dilution | ELISA (1:64000), IHC-P (3.75 µg/ml), WB (0.1-1 µg/ml) |
Gene ID | 81567 |
---|---|
Other Names | Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, ER protein 46, ERp46, Thioredoxin-like protein p46, TXNDC5, TLP46 |
Target/Specificity | Human TXNDC5. This antibody is expected to be able to recognise both reported human isoforms, as represented by NP_110437.2; NP_001139021.1. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | TXNDC5 / ERP46 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TXNDC5 (HGNC:21073) |
---|---|
Synonyms | TLP46 |
Function | Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds. |
Cellular Location | Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:Q91W90, ECO:0000255|PROSITE-ProRule:PRU10138} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity).
References
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Lo S.L.,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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