|Application ||IHC-P, E|
|Reactivity||Human, Horse, Dog|
|Dilution||ELISA (1:2000), IHC-P (3.75 µg/ml),|
|Other Names||ATP-binding cassette sub-family A member 2, ATP-binding cassette transporter 2, ATP-binding cassette 2, ABCA2, ABC2, KIAA1062|
|Target/Specificity||Human ABCA2. This antibody is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ABCA2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.|
|Cellular Location||Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Forms discrete, punctate intracellular vesicles|
|Tissue Location||Highly expressed in the brain, whereas lower levels of expression is observed in kidney and liver|
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Provided below are standard protocols that you may find useful for product applications.
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Kaminski W.E.,et al.Biochem. Biophys. Res. Commun. 281:249-258(2001).
Vulevic B.,et al.Cancer Res. 61:3339-3347(2001).
Humphray S.J.,et al.Nature 429:369-374(2004).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
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