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MTHFR Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | P42898 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 75kDa |
| Dilution | ELISA (1:16000), IHC-P (3.75 µg/ml), |
| Gene ID | 4524 |
|---|---|
| Other Names | Methylenetetrahydrofolate reductase, 1.5.1.20, MTHFR |
| Target/Specificity | Human MTHFR. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | MTHFR Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MTHFR (HGNC:7436) |
|---|---|
| Function | Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine (PubMed:29891918). Represents a key regulatory connection between the folate and methionine cycles (Probable). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.
References
Rozen R.,et al.Patent number WO9533054, 07-DEC-1995.
Goyette P.,et al.Mamm. Genome 9:652-656(1998).
Homberger A.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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