|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0-0.01 µg/ml)|
|Other Names||Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TPPP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Seki N.,et al.J. Hum. Genet. 44:121-122(1999).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Lindersson E.,et al.J. Biol. Chem. 280:5703-5715(2005).
Vincze O.,et al.Biochemistry 45:13818-13826(2006).
Olah J.,et al.FEBS Lett. 580:5807-5814(2006).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.