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TPPP Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - TPPP Antibody (Internal) ALS15786
    TPPP antibody (0.001 ug/ml) staining of Human Cerebellum lysate (35 ug protein/ml in RIPA buffer).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O94811
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 24kDa
Dilution ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0-0.01 µg/ml)
Additional Information
Gene ID 11076
Other Names Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1
Target/Specificity Human TPPP.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsTPPP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TPPP
Synonyms TPPP1
Function May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

References

Seki N.,et al.J. Hum. Genet. 44:121-122(1999).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Lindersson E.,et al.J. Biol. Chem. 280:5703-5715(2005).
Vincze O.,et al.Biochemistry 45:13818-13826(2006).
Olah J.,et al.FEBS Lett. 580:5807-5814(2006).

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$ 395.00
Cat# ALS15786
Size:
Quantity:
(40 western blots)
Availability: 5 days
Bulk Size
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