|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:20000), IHC-P (20 µg/ml), WB (1:500-1:1000)|
|Other Names||Steroid 21-hydroxylase, 22.214.171.124, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21, Cytochrome P450-C21B, CYP21A2, CYP21, CYP21B|
|Target/Specificity||Cytochrome P450 21A2 Antibody detects endogenous levels of total Cytochrome P450 21A2 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||CYP21A2 Antibody (aa151-200) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids (PubMed:22014889).|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
Higashi Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:2841-2845(1986).
White P.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:5111-5115(1986).
Rodrigues N.R.,et al.EMBO J. 6:1653-1661(1987).
Globerman H.,et al.J. Clin. Invest. 82:139-144(1988).
Helmberg A.,et al.Mol. Endocrinol. 6:1318-1322(1992).
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