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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Carboxypeptidase E / CPE Antibody (aa271-320)   

Carboxypeptidase E / CPE Antibody (aa271-320)

Rabbit Polyclonal Antibody

  • IHC - Carboxypeptidase E / CPE Antibody (aa271-320) ALS15803
    Anti-Carboxypeptidase E / CPE antibody IHC staining of human pancreas, islet.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16870
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution ELISA (1:5000), IHC-P (20 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 1363
Other Names Carboxypeptidase E, CPE,, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase, CPE
Target/Specificity CPE Antibody detects endogenous levels of total CPE protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsCarboxypeptidase E / CPE Antibody (aa271-320) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPE
Function Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
Cellular Location Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
Tissue Location Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas
Volume 50 µl
Research Areas
Citations (0)

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Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.


Manser E.,et al.Biochem. J. 267:517-525(1990).
Utsunomiya N.,et al.Diabetologia 41:701-705(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lee T.K.,et al.J. Clin. Invest. 121:880-892(2011).

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$ 395.00
Cat# ALS15803
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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